Increase of Dialysate Dopamine in the Bed Nucleus of Stria Terminalis by Clozapine and Related Neuroleptics
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چکیده
منابع مشابه
Stimulation of in vivo dopamine transmission in the bed nucleus of stria terminalis by reinforcing drugs.
Drugs of abuse preferentially increase dopamine transmission in the shell of the nucleus accumbens. This area is considered as a transition between the striatum and the extended amygdala a complex neural system that includes the central amygdala and the bed nucleus of stria terminalis, areas that, like the nucleus accumbens shell, are heavily innervated by mesolimbic dopamine neurons originatin...
متن کاملPotent regulation of midbrain dopamine neurons by the bed nucleus of the stria terminalis.
Recent studies have revealed an important role of the ventrolateral (subcommissural) aspect of the bed nucleus of the stria terminalis (vBNST) in motivational aspects of drug abuse (Delfs et al., 2000). Dopaminergic (DA) neurons in the ventral tegmental area (VTA) have also long been linked to motivation and drug abuse (Koob and Le Moal, 2001). The present study tested whether activity in the v...
متن کاملRole of GABAA receptors of bed nucleus stria terminalis in controlling of blood pressure and heart rate in rats
Introduction: The Bed nucleus stria terminalis (BST) is a part of the limbic system. It was recently shown that chemical stimulation of the BST by L-glutamate elicited cardiovascular depressive responses. In the present study, we have investigated the possible cardiovascular role of the GABAergic receptors in BST by microinjection of its agonist and antagonists. Methods: Experiments were p...
متن کاملOrbitofrontal cortex lesions alter anxiety-related activity in the primate bed nucleus of stria terminalis.
In children, behavioral inhibition (BI) in response to potential threat predicts the development of anxiety and affective disorders, and primate lesion studies suggest involvement of the orbitofrontal cortex (OFC) in mediating BI. Lesion studies are essential for establishing causality in brain-behavior relationships, but should be interpreted cautiously because the impact of a discrete lesion ...
متن کاملاثرات داروهای هیستامینرژیک در bed nucleus of the stria terminalis (bnst) رت ها در تست elevated plus maze بر رفتارهای شبه اضطرابی
سیستم هیستامینرژیک مرکزی دارای تاثیرات تنظیمی بر رفتارهای شبه اضطرابی هم در حیوانات و هم در انسان است. این تاثیرات از طریق رسپتور h1 و h2 میانجیگری میشود. تست epm(elevatd plus-maze( برای بررسی تاثیرات اضطراب زایی یا اضطراب زدایی داروها در جوندگان بکار میرود. شواهد نشان می دهند که فعالیت (bnst) bed nucleus the stria terminalis رفتار شبه اضطرابی را در انسانها و حیوانات تنظیم می کند. در مطالعه حاض...
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ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2000
ISSN: 0893-133X
DOI: 10.1016/s0893-133x(99)00085-8